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V-SIS GENES
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DeCS
Descriptor
English
:
Genes, sis
Descriptor
Spanish
:
Genes sis
Descriptor
Portuguese
:
Genes sis
Synonyms
English
:
c-sis Genes
sis Genes
v-sis Genes
Genes, PDGFB
Tree Number:
G14.340.024.340.383.500.791.560
Definition
English
:
Retrovirus-associated
DNA
sequences (v-sis) originally isolated from the simian
sarcoma
virus (SSV). The proto-oncogene c-sis
codes
for a
growth
factor which is the B chain of
PLATELET-DERIVED GROWTH FACTOR
. v-sis or overexpression of c-sis causes tumorigenesis. The human sis gene is located at 22q12.3-13.1 on the long
arm
of chromosome 22.
See Related
English
:
Oncogene Proteins v-sis
Proto-Oncogene Proteins c-sis
History Note
English
:
2000; use ONCOGENES 1988-1999
Allowable Qualifiers
English
:
drug effects
ethics
genetics
immunology
physiology
radiation effects
Record Number:
34578
Unique Identifier:
D020571
Occurrence in VHL
:
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